Food Allergy Testing is a refined way to support people with specific allergies when broad based attempts to eliminate particular foods do not lead to results.
Often results of test are a huge list of incompatible foods and nothing left to eat – making compliance too hard.
New and advanced tests can ascertain severe food allergies that need to be adhered to and minor reactivity that can be addressed by rotating foods.
Sometimes food allergies are mixed up with histamine intolerances (*)
Call us now on 08 63802643 and discover your individual optimal food panel
If you are interested in technical background info, keep reading:
Controversy IgG vs IgG4
Dr.Camille Lieners) describes the difference of food allergy mediated by IgE and delayed food allergy mediated by IgG. A major difference between several tests on the market is the type of IgG tested. IgG is divided in 4 subclasses, IgG1, IgG2, IgG3 and IgG4.
IgG4 is related to a type 1 allergy and can be considered as the antidote of IgE. IgG4 does not opsonise (make bacteria or other cells more susceptible to the action of phagocytes) the antigen and does not activate the complement. IgG4 is a scavenging antibody not inducing inflammation. IgG1, IgG2 and IgG3 have all opsonising properties and are able to activate the complement, necessary for an inflammatory response. IgG4 is not recommended for the detection of adverse food reactions.
IgG4 is present in blood in much lower concentrations than the other subclasses.
The sensitivity of ImuPro 300 test towards IgG4 is adjusted in a way to only detect very high levels of IgG4, commonly reported as RAST class 6. This is important because lower values of IgG4 are irrelevant, but higher values of IgG4 could generate histamine, which could lead to pseudo-allergic symptoms (*)
Therefore it is preferable to avoid these foods too. Dr Camille Lieners believes the main reason for the present controversy is that the allergy societies confuse specific total IgG testing with IgG4 testing, considered as useless in allergic diseases. In most publications in allergy research IgG4 was used as marker.
The high consistency and the reproducibility of the ImuPro 300 test have made IgG testing reliable and a new powerful tool to fight chronic inflammatory diseases by an individualized elimination diet.
Adapted from: IgG food intolerance: A controversial discussion by Dr.Camille Lieners, ImuPro Science
(*) Histamine intolerance is caused by a deficiency/inhibition of the enzyme diamine oxidase (DOA). If a DOA deficiency is present the body will not be able to degrade fast enough histamine taken in food or released by the body and intolerance symptoms will occur: