Mauve Factor/Pyrrole Disorder

Mauve Factor/Pyrrole Disorder is a genetically based condition. Affected people produce excessive amounts of a metabolite called hydroxyhemopyrolin-2-one (HLP).

HLP or Mauve Factor interferes and binds to essential nutrients like zinc and B6 (and more) and renders them unavailable to the body. The vitamins and minerals bound to HLP are excreted from the body via urine, resulting in a deficiency.

There are also associated changes in fatty acid metabolism, causing lower levels of arachidonic acid.

Even so there is a genetic disease base the onset usually requires a traumatic event.

Many conditions like ADD/ADHD, Tourette syndrome, alcoholism, severe depression, bipolar disorder and schizophrenia are now thought to may be different manifestations of HLP.

Some characteristics of elevated HLP reading include:

  • White spots on fingernails
  • Tremor, shaking
  • Stress intolerance
  • Emotional instability
  • Explosive anger
  • Anxiety, withdrawal
  • Substance abuse
  • Severe hypoglycaemia/glucose intolerance
  • Joint pain
  • Stretch marks
  • Reduce morning food tolerance

Be aware that all of these symptoms can be caused by a variety of other conditions.

To exclude Pyrrole disorder a simple urine test can be done.

The decisive laboratory test is analysis for kryptopyrroles in urine. Treatment is centred on zinc and B6 supplements together with B3 and omega-6
essential fatty acids. If left undiagnosed and untreated, the condition can lead to a wide range of significant health problems, with adults showing increased

Because the treatment has a metabolic rather than pharmacologic basis, it must be tailored to individual requirements. A variety of factors need to be  taken into consideration when developing a treatment regimen.